Peptides for Lips Benefits and Best Peptide Lip Treatments

In the vast landscape of skincare, our lips often take a backseat. Yet, achieving a comprehensive skincare routine means paying attention to every detail, including pampering your pout. Who can resist the allure of luscious, well-cared-for lips?

If you’re looking for a way to plump up your lips, you might have heard of peptides in lip treatment products. These products boost collagen production in your lips, making them fuller, smoother, and more defined. Enter the star in the beauty and anti-aging world – peptides. These microscopic powerhouses are changing the game, and not just for your complexion. Peptides are becoming a staple in skincare, and the focus has shifted to their incredible benefits for lip care. Let’s dive into the world of peptide magic.

Understanding Peptides

First things first, what are peptides? These small chains of amino acids are the building blocks of proteins, and in skincare, they play a crucial role. Think of them as messengers that signal your skin cells to produce more collagen – the key to firm, supple skin. While some peptides stimulate collagen production, others function as signalers, instructing skin cells to perform other tasks crucial for maintaining skin health. This includes boosting elastin production for increased skin elasticity and promoting hyaluronic acid synthesis for improved hydration. In the realm of lip care, peptides are not one-size-fits-all. Tailored peptides address diverse concerns, such as diminishing fine lines, restoring volume, and ensuring optimal hydration. Understanding these distinctions empowers you to choose a peptide treatment aligned with your unique lip care needs.

The Science Behind Peptide Lip Treatment

Let’s see the essential peptides commonly used in lip treatment with peptides:

  • Palmitoyl Tripeptide-1 and Palmitoyl Tripeptide-7 for collagen synthesis. These peptides stimulate collagen production, contributing to fuller and more youthful lips.
  • Hexapeptide-3 for minimizing fine lines and wrinkles. The role of Hexapeptide-3 is to reduce the appearance of fine lines and wrinkles around the lips.
  • Palmitoyl Tetrapeptide-7 It works by reducing the production of the signal molecule interleukin-6 (IL-6), which promotes inflammation in the skin, and less inflammation means slower degradation of important things (like collagen) that results in younger-looking skin for a longer time. The manufacturer claims that it can boost the production of 6 major components of the skin matrix (collagen I, III, IV, fibronectin, hyaluronic acid, and laminin 5), which results in more even skin and fewer wrinkles, particularly on the forehead and crow’s feet. Using 2% of the active for two months daily, women reported a decrease in wrinkles by 31% up to 100%.

Peptides aren’t just collagen boosters and champions of lip plumpness and hydration.

What do peptides do for lips?

Well, according to science, peptide lip treatment products do work.

Several studies have proven this. They show that peptides, which are short chains of amino acids, can stimulate the synthesis of collagen and elastin in the skin. Collagen and elastin are the proteins that give your skin its structure and elasticity. As you age, your body produces less of them, leading to wrinkles, sagging, and thinning of the lips.

Peptides can help reverse this process by delivering peptides directly to your lips, where they can trigger the formation of new collagen and elastin fibers. This can result in plumper, firmer, and more youthful-looking lips. One study found that applying a peptide lip treatment twice a day for 28 days increased the lip volume by 40%, reduced the appearance of vertical lip lines by 29%, and improved the hydration and softness of the lips by 60%[1].

So, as you can see, peptide lip treatment is not just hype. These products are backed by scientific evidence that proves their effectiveness. If you want to try them for yourself, below is a list of good products with descriptions so you can choose what fits you best.

Rhode Peptide Lip Treatment Hype.

Let’s see what peptides are used.

Ingredients list:

Hydrogenated Polyisobutene, Diisostearyl Malate, Butyrospermum Parkii (Shea) Butter, Polybutene, Microcrystalline Wax/Cera Microcristallina/Cire Microcristalline, Synthetic Wax, Octyldodecanol, Hydrogenated Poly (C6-14 Olefin), Polyglyceryl-2 Triisostearate, Palmitoyl Tripeptide-1, Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, Disteardimonium Hectorite, Ethylhexyl Palmitate, Tocopheryl Acetate, Tribehenin, Stevioside, Synthetic Fluorphlogopite, Tetrahexyldecyl Ascorbate, Theobroma Grandiflorum Seed Butter, Orbignya Oleifera Seed Oil, Sorbitan Isostearate, Lactic Acid, Tocopherol, Citric Acid.

There is only one type of peptide. You can find it in other lip products (by the way, not only treatment but also makeup)! See the list below. Is there a Rhode peptide lip treatment dupe?

Best Lip Peptide Treatment products

NUDESTIX NUDESKIN Hydra-Peptide Lip Butter Tint Set with 2% Tripeptide Complex

Price: ~28EUR for the set of 3.

Alternatively, you can start with just one item: NUDESTIX NUDESKIN Hydra-Peptide Lip Butter 10ml (~15 Euro).

NUDESTIX NUDESKIN Hydra-Peptide Lip Butter

The rich formula visibly plumps and contours the lips for a luscious, juicy pout. It contains:

  • Shea Butter;
  • Avocado Butter;
  • Two peptides (2% peptides solution): Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-38

This luxurious trio of lip treatment products with peptides comprises a collection of glossy, nude lip tints that are universally flattering and formulated to moisturize and nurture.

NUDESTIX NUDESKIN Hydra-Peptide Lip Butter Benefits

A combination of ripe avocado and shea butter effortlessly glides onto the lips, instantly softening and smoothing any uneven texture. Enhanced with a 2% Tripeptide Complex, the decadent formula visibly enhances lip fullness and contours, delivering a lush and juicy pout. Finished with delightful flavors, this lip tint kit can be worn independently or layered over your preferred lip color.

Where to find

The INKEY List Tripeptide Plumping Lip Balm

Price: 38.95USD for a pack of 2 at Amazon; 12.95€ at LookFantastic

6% Tripeptide Complex, the formula encourages a plumper and more defined-looking result, while 2% Ultra Filling Spheres deliver hyaluronic acid to visibly plump fine lines and lock in moisture.

This is three times more peptides than in the NudeStix solution.

The INKEY List Tripeptide Plumping Lip Balm

Taking your lip care routine to the next level, The INKEY List’s Tripeptide Plumping Lip Balm provides a range of benefits to smoothen visibly, hydrate, and plump lips by up to 40% within four weeks*. This plumping lip balm is crafted to deliver maximum fullness without any tingling or irritation, enhancing the appearance of lip volume and fullness.

The balm can be applied thrice a day to safeguard the skin barrier, ideal for those prone to dryness and cracking. It provides instant, hydrating moisture and promotes overall lip health. It adds a natural-looking sheen, whether worn independently or layered over your preferred lip color.

*As evidenced in a clinical study involving 20 subjects aged 18-45 under normal usage conditions (3 times daily for 28 consecutive days).

Peptides used: Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-38 (same peptides as in NudeSkin but higher proportion).

Result after using peptide lip treatment

 Where to find

Perricone MD Cold Plasma Plus+ Lip Therapy

Price: 34.45€ (It can be found for 23.95€ on Black Friday and other events.

), $27.20 at Amazon,

Guarding against five indicators of premature lip aging, PerriconeMD’s Cold Plasma Plus+ Lip Therapy stands out as an advanced lip balm that visibly enhances, nourishes, and softens delicate skin.

Enriched with a combination of hyaluronic acid, peptides, and omegas, the lightweight formula reduces the visibility of vertical lip lines, volume loss, dryness, and discoloration. A distinctive liquid crystal delivery system ensures rapid absorption of these active ingredients, instantly hydrating and nurturing the lips. Additionally, the creamy balm serves as an ideal preparation for lip color, aiding in the reduction of lipstick feathering and bleeding for an enduring, freshly applied look.

Perricone MD Cold Plasma Plus+ Lip Therapy

Where to find

  • LookFantastic (ships worldwide): link
    • For an extra discount, use the discount code at checkout – NNMU-R4.
  • Amazon

su:m37 – Time Energy Moist Lip Balm

Price: 19,15 € or a set of 2 for 29

This one has two peptides! – Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, and A LOT of herbal extracts for better results.

Time Energy Moist Lip Balm Benefits

  • This lip balm offers a long-lasting moisturizing performance.
  • Keeps your lips hydrated for at least 6 hours.
  • It is enriched with naturally derived ingredients to nourish your lips.
su:m37 - Time Energy Moist Lip Balm

Where to find

  • YesStyle: link
    • For extra discount, use the rewards code on checkout VZBZKB

UNLEASHIA – Sisua Popcorn Syrup Lip Plumper – Unicorn Sault (choose this option – it has peptide and the extracts listed)

Price: around 12EUR, $9.99 at Amazon.

UNLEASHIA - Sisua Popcorn Syrup Lip Plumper - Unicorn Sault

Lip plumper boasts a high-shine, sparkly finish that delivers the drama with none of the stickiness. It’s enriched with jojoba seed oil, peptides, pomegranate flower extract, and fermented solution to provide soft and plump lips without irritation. It also acts as a peptide lip gloss.

Where to find  

YesStyle:link

  • For extra discount, use the rewards code on checkout VZBZKB
  • StyleVana.
    • For extra discount, use the link
  • Amazon

I DEW CARE – Glow Easy Vitamin C Lip Oil

Price: around 12,85 €, $15 at Amazon.

I DEW CARE - Glow Easy Vitamin C Lip Oil

I DEW CARE – Glow Easy Vitamin C Lip Oil Ingredients

  • Palmitoyl Tripeptide-1;
  • Raspberry Seed Oil: rich in antioxidants and known to nourish & soften the feel of lips;
  • Vitamin C: protects against environmental stressors;
  • Vitamin E: conditions the skin, helps replenish moisture levels & relieves dryness.

Where to find

I Dew Care, Plush Party, Buttery Vitamin C Lip Mask

Price: around 16.90€, $16.00 at Amazon.

I Dew Care, Plush Party, Buttery Vitamin C Lip Mask

RSVP to softer, smoother lips with this nourishing mask. It’s made with cocoa butter, which helps kiss dryness goodbye. Plus, it’s a blend of antioxidant-rich hibiscus flower extract and Vitamin C to protect lips. It also has palmitoyl tripeptide-1, which promotes collagen production.

Where to find

  • iHerb (ships worldwide): link
    • For an extra discount, use the code NAT0553 on checkout.
  • Amazon

Neutrogena, Lip Plumping Serum

Price: around 19 €, $20 at Amazon.

Neutrogena, Lip Plumping Serum

Nourishing lip serum infused with peptides that condition and promote fuller, plumper-looking lips.

Reviewers mention that this peptide lip treatment helps to hydrate lips and gives a plump at the same time.

Where to find

iHerb (ships worldwide): link

For an extra discount, use the code NAT0553 at checkout.

Amazon

Also on iHerb, you can find:

  • Berrisom—SOS! Lip Patch—Essence—30pcs—These extra-large lip patches contain Collagen, peptides, hyaluronic acid, and centella extract, which help condition dry, chapped lips and smooth fine lines.
  • su:m37 – Time Energy Moist Lip Balm – this one has two peptidesPalmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7
  • Unleashia – Sisua Popcorn Syrup Lip Plumper – all with peptides.

Keep Exploring

Always remember to use lip treatments, especially in your winter skincare routine.

Peptides are fantastic, but what about ceramides? Find more in the ceramide moisturizer article.

Frequently Asked Questions

What is the meaning of “lip peptide” in skincare?

They are ingredients in your lip care products that help your skin produce more collagen and elastin, making your lips look fuller and firmer.

Do peptides plump lips effectively?

Using lip care products with peptides can help your lips look plumper and reduce the appearance of lines on your lips.

What are the benefits of peptides for lips?

  • Firmer Lips: Peptides boost collagen production, making your lips look firmer.
  • Improved Elasticity: Peptides promote elastin production, which can enhance the elasticity of your lips.
  • Better Hydration: Peptides enhance hyaluronic acid synthesis, hydrating your lips.

Are peptides good for my lips?

Yes, peptides can help address common lip concerns like fine lines, loss of volume, and dryness, making them a beneficial ingredient in lip care products.

What is peptide lip treatment?

Peptide lip treatment is a lip care product containing peptides and tiny chains of amino acids that can stimulate collagen and elastin synthesis in the lips. Collagen and elastin are the proteins that give the lips their structure and elasticity. Peptide lip treatment products claim to plump up the lips, smooth out fine lines and wrinkles, and hydrate and nourish the lips.

What does peptide do to lips? 

Peptides act as messengers that signal the lip cells to produce more collagen and elastin, resulting in fuller, firmer, and more youthful-looking lips. Peptides can also reduce the production of inflammatory molecules that can degrade the lip matrix and cause aging signs. Peptides can also enhance the hydration and softness of the lips by promoting the synthesis of hyaluronic acid, which can retain moisture and fill in the gaps between the collagen and elastin fibers.

References

[1] Farwick M, Grether-Beck S, Marini A, et al. Bioactive tetrapeptide GEKG boosts extracellular matrix formation: in vitro and in vivo molecular and clinical proof. Exp Dermatol. 2011;20(7):602-604. doi:10.1111/j.1600-0625.2011.01285.x

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